Status:
COMPLETED
Hemostatic Endothelial Dysfunction in Patients With Peripheral Artery Disease
Lead Sponsor:
Ryazan State Medical University
Conditions:
Peripheral Artery Disease
Restenosis of Peripheral Vascular Stent
Eligibility:
All Genders
40-85 years
Brief Summary
The study is aimed at evaluating the role of the activity of the key hemostatic parameters of endothelial dysfunction (nitric oxide II (NO) metabolites, plasmin activator inhibitor-1 (PAI-1), von Will...
Detailed Description
The study will involve patients with atherosclerotic peripheral artery disease (Rutherford category 3-5). The subjects are to be divided into three groups: Group A: patients who undergo bypass surger...
Eligibility Criteria
Inclusion
- Males or females older than 40 years of age;
- Presence of peripheral arterial disease of atherosclerotic origin.
Exclusion
- Males or females younger than 40 years of age;
- Chronic lower limb ischemia of other ethiology (Buerger's disease, aortoarteritis etc.);
- Active cancer or remission period less than 5 years;
- Decompensated diabetes mellitus;
- Pregnancy or breast-feeding for females.
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 23 2023
Estimated Enrollment :
167 Patients enrolled
Trial Details
Trial ID
NCT04391374
Start Date
January 1 2017
End Date
March 23 2023
Last Update
May 3 2023
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