Status:
RECRUITING
Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate
Lead Sponsor:
University of Calgary
Conditions:
Cerebrovascular Circulation
Physiology
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The investigators will seek to determine the relationship between heart rate and middle cerebral artery (MCA) cerebral blood flow (CBF), as well as better understand the hemodynamic determinants of MC...
Detailed Description
Background: Cerebral blood flow (CBF) is maintained at a relatively constant level by multiple overlapping auto-regulatory systems over a wide range of blood pressures. This ensures adequate oxygen de...
Eligibility Criteria
Inclusion
- Male or female
- Age 18-70 years, inclusive
- Scheduled for clinically indicated elective electrophysiological studies where temporary pacing catheters are being placed in the right atrium
- Left ventricular ejection fraction ≥50%
- Able and willing to provide informed consent
- Able to travel to the Cardiac Electrophysiology Laboratory at the Foothills Medical Centre, Calgary, Alberta, Canada
Exclusion
- Unable or unwilling to provide informed consent
- Other factors which in the investigator's opinion would prevent the participant from completing the protocol
Key Trial Info
Start Date :
August 11 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04391465
Start Date
August 11 2021
End Date
June 1 2027
Last Update
May 9 2024
Active Locations (1)
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1
Foothills Medical Center
Calgary, Alberta, Canada, T2N 4Z6