Status:
UNKNOWN
Predicting Locally Advanced Rectal Cancer Response to NCT and NCRT With MRI
Lead Sponsor:
Ziqiang Wang,MD
Conditions:
Rectal Cancer
MRI
Eligibility:
All Genders
Brief Summary
This trial was designed to to study whether there is a difference in MRI image evaluation between NCRT and NCT, and try to build a model to predict the efficacy of neoadjuvant therapy by combining mul...
Detailed Description
This study was designed as a retrospective case-control study. All 116 patients with locally advanced rectal cancer who started neoadjuvant chemoradiotherapy and underwent radical surgery in West of C...
Eligibility Criteria
Inclusion
- pathological diagnosis of rectal cancer;
- received neoadjuvant chemoradiotherapy before surgery;
- before neoadjuvant therapy and before surgery, the patients received thin and high resolution MRI examination of the rectum.
- before neoadjuvant therapy, colonoscopy, rectal contrast-enhanced ultrasound or MRI showed that the lower margin of the tumor was within 12cm from the anal margin;
- pre-neoadjuvant clinical stage II/III (AJCC 7th edition);
Exclusion
- simultaneous distant metastatic tumor should be considered at the first diagnosis;
- patients with distant metastasis were not considered at the initial diagnosis;
- with other malignant tumors;
- before neoadjuvant therapy, patients had received other relevant treatments;
- to undergo palliative surgery or emergency surgery in the course of neoadjuvant therapy;
Key Trial Info
Start Date :
January 15 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 15 2020
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT04392609
Start Date
January 15 2020
End Date
July 15 2020
Last Update
May 19 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Guoxue Road 37#,West China Hospital
Chengdu, Sichuan, China, 610041