Status:
TERMINATED
COVID Cohort Study
Lead Sponsor:
University of Vermont
Conditions:
COVID-19
Acute Respiratory Failure
Eligibility:
All Genders
18+ years
Brief Summary
The novel SARS-CoV-2 virus has quickly spread worldwide, with substantial morbidity and mortality. There is very limited understanding of the short- and longer-term inflammatory/immunological and clin...
Detailed Description
The novel coronavirus (SARS-CoV-2) and associated COVID-19 illness has quickly spread worldwide, with substantial morbidity and mortality. Early data suggest that most patients with severe COVID-19 (i...
Eligibility Criteria
Inclusion
- Adult (≥18 years old) at the time of consent
- Positive COVID-19 test result or highly suspicious for COVID-19 infection and have a test pending
- Acute Respiratory Failure (new requirement for supplemental oxygen or acute increase in required supplemental oxygen)
Exclusion
- Expected death or withdrawal of life-sustaining treatments within 3 days
- Unable to walk ≥150 feet prior to COVID-19 (due to 6-minute walk test being primary outcome for in-person testing)
- Hemoglobin ≤7.0 at the time of consent
- Pre-existing cognitive/language impairment prohibiting clinical outcomes assessment
- Prior lung resection (due to spirometry as part of in-person outcome assessment)
- Unable to provide consent and no legally authorized representative (LAR) identified or reached by phone
- Pregnant
- Incarcerated
- Homelessness
- Physician declines patient enrollment (attending physician or study physician)
- Patient or LAR do not consent to participate in the study
Key Trial Info
Start Date :
April 16 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 25 2021
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT04393155
Start Date
April 16 2020
End Date
January 25 2021
Last Update
February 12 2021
Active Locations (1)
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1
University of Vermont College of Medicine
Burlington, Vermont, United States, 05405