Status:

UNKNOWN

Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population

Lead Sponsor:

St. Justine's Hospital

Collaborating Sponsors:

Ciusss de L'Est de l'Île de Montréal

Conditions:

Adverse Drug Event

Eligibility:

All Genders

Up to 18 years

Brief Summary

Introduction: Second Generation Antipsychotics (SGAs) are widely used in the pediatric population. It is currently established that SGAs may induce undesirable metabolic adverse events (AEs) such as w...

Detailed Description

Objectives The primary objective is to study selected factors that can influence the development of the SGA's metabolic AEs such as the main diagnosis for which the SGA is prescribed, comorbidities, t...

Eligibility Criteria

Inclusion

  • patients under 18 years of age,
  • previously AP-naifs,
  • starting an SGA or who started an SGA for less than 4 weeks,
  • followed longitudinally at one of the selected recruiting center,
  • regardless of the diagnosis that motivated the prescription of the SGA medication.

Exclusion

  • diabetes,
  • dyslipidemia,
  • high blood pressure,
  • thyroid dysfunction,
  • hepatic disease,
  • hyperprolactinemia,
  • taking a medication to treat any of the above conditions before starting SGA treatment and pregnancy.

Key Trial Info

Start Date :

January 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT04395326

Start Date

January 1 2017

End Date

December 31 2025

Last Update

May 20 2020

Active Locations (1)

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Ben Amor Leila

Montreal, Quebec, Canada, H3T 1C5