Status:

UNKNOWN

Measurement of Lung Area at Chest Radiography to Define the Prognosis in Newborns With CDH

Lead Sponsor:

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Conditions:

Congenital Diaphragmatic Hernia

Eligibility:

All Genders

1-24 years

Brief Summary

CDH represents a malformative disorder characterized by an incomplete diaphragm formation. This results in poor lung development (pulmonary hypoplasia), associated with altered vascularization of the ...

Detailed Description

The study period considered will be January 2012 - December 2018. From the medical record of each patient, the investigators will collect the following data: prenatal history, hernia severity, fetal e...

Eligibility Criteria

Inclusion

  • Inborn and outborn patients admitted to the NICU within 24 hours after birth.
  • Prenatal or postnatal (within 24 hours after birth) diagnosis of CDH.
  • Preoperative chest radiograph performed for clinical purposes within 24 hours after birth in our NICU.

Exclusion

  • Diagnosis of CDH made beyond 24 hours after birth
  • Admission to the NICU beyond 24 hours after birth
  • Preoperative chest radiograph performed beyond 24 hours after birth, rotated/asymmetric, with air leak (pneumothorax, pneumoperitoneum), not performed in our NICU or not accessible
  • Early death (within 1 hour after birth)

Key Trial Info

Start Date :

July 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

85 Patients enrolled

Trial Details

Trial ID

NCT04396028

Start Date

July 9 2020

End Date

December 31 2021

Last Update

August 24 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Milan, MI, Italy, 20129