Status:
UNKNOWN
Multicenter Normal Reference Study of Tissue Motion Tracking of Mitral Annular Displacement(TMAD)
Lead Sponsor:
Weidong Ren
Conditions:
Left Ventricular Systolic Dysfunction
Healthy Volunteers
Eligibility:
All Genders
18-79 years
Brief Summary
To establish the range of TMADmid、TMADmidpt% by using tissue motion tracking of mitral annular displacement (TMAD), and to explore the influencing factors.
Detailed Description
With the gradual aging of Chinese population and continuous development of economy and society, the incidence of cardiovascular disease and the number of patients have increased rapidly. The National ...
Eligibility Criteria
Inclusion
- Han nationality
- Ages 18-79.
- Normal body mass index (18-25kg / m2).
- Normal blood pressure (139-90 / 89-60mmHg).
- No history of cardiovascular and respiratory diseases.
- No abnormality was found in physical examination of cardiovascular and respiratory system.
- Blood glucose, lipid profile and electrocardiogram were normal.
- Echocardiography showed no structural heart disease and normal heart function.
- No history of medications affecting cardiovascular system.
Exclusion
- Clinically significant or moderate heart valve regurgitation.
- Respiratory diseases: acute or chronic respiratory diseases.
- Endocrine diseases: thyroid disease, diabetes, hyperaldosteronism, pheochromocytoma, and abnormal adrenal function.
- Anemia.
- Pregnant or lactating women.
- Abnormal liver function (glutamyl aminotransferase exceeds 2.0 times the upper limit of normal value), abnormal renal function (creatinine exceeds the normal value), increased blood lipids (triglycerides, total cholesterol, low density and high density lipoprotein, any of which is higher than Normal value).
- Connective tissue disease.
- Tumor.
- Aortic and peripheral vascular diseases: aortic dilatation, aortic dissection, aortic constriction, multiple arteritis, and atherosclerosis.
- Drink more than 50ml of white wine daily; more than 100ml of red wine; more than 300ml of beer.
- Professional athletes.
- The poor quality of the ultrasound image cannot satisfy the parameter measurement and analysis.
Key Trial Info
Start Date :
June 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2021
Estimated Enrollment :
2400 Patients enrolled
Trial Details
Trial ID
NCT04399447
Start Date
June 1 2020
End Date
September 30 2021
Last Update
May 22 2020
Active Locations (76)
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Anhui Provincial Hospital
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