Status:

COMPLETED

Antibiotic Selection Using Next Generation Sequencing vs Urine Culture

Lead Sponsor:

The University of Texas Health Science Center at San Antonio

Collaborating Sponsors:

Microgen LLC

Conditions:

Kidney Stone

Renal Stone

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a randomized controlled clinical study evaluating the use of next-generation sequencing (NGS) to improve antibiotic prescribing before ureteroscopy or percutaneous nephrolithotomy.

Detailed Description

NGS will be performed on voided urine collected as routine care approximately 30 days prior to surgery. Results will be presented to Infectious Disease pharmacist within 48-72 hours to help select the...

Eligibility Criteria

Inclusion

  • Patients planning to undergo kidney or bladder stone removal surgery using endoscopy including ureteroscopy and percutaneous nephrolithotomy or any other transurethral procedure
  • Age 18 or older
  • Able to give informed consent

Exclusion

  • Unwilling or unable to provide informed consent
  • Age \< 18
  • Does not meet inclusion criteria

Key Trial Info

Start Date :

December 18 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2022

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT04404855

Start Date

December 18 2019

End Date

August 31 2022

Last Update

March 12 2024

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Audie Murphy VA Hospital

San Antonio, Texas, United States, 78229

2

The University of Texas Health Science Center at San Antonio, Medical Arts and Research Center

San Antonio, Texas, United States, 78229

3

University Health System

San Antonio, Texas, United States, 78229