Status:

COMPLETED

The Application of Non-invasive and Cellular Level Resolution Fullfield Optical Coherence Tomography: Establishment and Analysis of Subcutaneous Cellular Level Image Database of Anatomical Locations in Healthy Volunteers and Evaluation of Usability

Lead Sponsor:

Taipei Veterans General Hospital, Taiwan

Collaborating Sponsors:

Apollo Medical Optics, Ltd

Conditions:

Healthy Skin

Nevus

Eligibility:

All Genders

Brief Summary

ApolloVue® S100 Image System is a medical device class II. The objective of this protocol is to image skin of healthy volunteers and to evaluate the performance of full-field optical coherence tomogra...

Detailed Description

The OCT can provide cellular resolution (\~1μm in lateral and axial directions) images. A cellular resolution OCT has the characteristics of non-invasive, non-radioactive, labelfree, real-time and hig...

Eligibility Criteria

Inclusion

  • All age will be recruited.
  • Both genders will be recruited.
  • All skin types will be recruited. Skin type I-VI (Fitzpatrick scale)
  • Type I always burns, never tans (unexposed skin color: white)
  • Type II usually burns, tans less than average (with difficulty) (unexposed skin color: white)
  • Type III sometimes mild burns, tans about average (unexposed skin color: white)
  • Type IV rarely burns, tans more than average (with easy) (unexposed skin color: white)
  • Type V very rarely burns (unexposed skin color: brown)
  • Type VI never burns (unexposed skin color: black)
  • Has healthy skin at 5 anatomical locations including face, back, dorsal forearm, volar forearm, and calf.
  • Has at least a nevus without superficial scales and crusting
  • Willing to provide informed consent

Exclusion

  • Individuals who have a systemic skin disorder.
  • Individuals who have a history of severe skin condition
  • Individuals with surgeries/cosmetic surgeries/micro cosmetic surgery (eg. cosmetic injections and/or laser etc.) on healthy skin at the 5 anatomical locations and nevi (see inclusion criteria 5) in last 12 months and a physician determine the surgery will affect outcome of the OCT images.
  • Not willing to cooperate with methods and related procedures of this trial/study

Key Trial Info

Start Date :

July 6 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 8 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04406454

Start Date

July 6 2020

End Date

February 8 2022

Last Update

November 14 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Taipei Veterans General Hospital

Taipei, Beitou District, Taiwan, 11217