Status:

COMPLETED

Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure

Lead Sponsor:

Columbia University

Conditions:

Oxygen Deficiency

Coronavirus Infection

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to retrospectively review clinical data to determine whether awake proning improves oxygenation in spontaneously breathing patients with COVID-19 severe hypoxemic respirat...

Detailed Description

Critically ill patients with coronavirus disease 2019 (COVID-19) severely strained intensive care resources in New York in April 2020. The prone position improves oxygenation in intubated patients wit...

Eligibility Criteria

Inclusion

  • Consecutive patients admitted to the Columbia University step-down unit from April 6, 2020.
  • Laboratory confirmed COVID-19 infection with severe hypoxemic respiratory failure defined as respiratory rate ≥30 breaths/min and oxyhemoglobin saturation (SpO2) ≤93% while receiving supplemental oxygen 6 L/min via nasal cannula and 15 L/min via non-rebreather facemask.

Exclusion

  • Altered mental status with inability to turn in bed without assistance
  • Extreme respiratory distress requiring immediate intubation, or oxygen requirements less than specified in the inclusion criteria.

Key Trial Info

Start Date :

April 16 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 6 2022

Estimated Enrollment :

29 Patients enrolled

Trial Details

Trial ID

NCT04408222

Start Date

April 16 2020

End Date

March 6 2022

Last Update

March 9 2022

Active Locations (1)

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1

Columbia University Irving Medical Center

New York, New York, United States, 10032