Status:

COMPLETED

Simplified Algorithm for the Prevention of Postoperative Nausea and Vomiting in an Oncological Hospital

Lead Sponsor:

Instituto do Cancer do Estado de São Paulo

Conditions:

Postoperative Nausea

Postoperative Vomiting

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Previous history of nausea and vomiting induced by prior chemotherapy still not included as predictive factor of postoperative nausea and vomiting, although has been demonstrated that has influence in...

Detailed Description

Quasi-experimental study, with evaluation after the application of a specific postoperative nausea and vomiting prevention algorithm for cancer patients. The study will be carried out in 2 phases: P...

Eligibility Criteria

Inclusion

  • All patients who underwent medium to large surgery

Exclusion

  • Patients who are unable to communicate (orotracheal intubation after the surgery, confusion or agitation) or understand the Portuguese language;
  • Insulin dependent patients
  • Patients who underwent emergency surgery and neurosurgery
  • Pacients who had an increased QT interval on the electrocardiogram
  • History of allergy to dexametasone, ondansetron or droperidol
  • Refusal to participate

Key Trial Info

Start Date :

February 20 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 20 2021

Estimated Enrollment :

270 Patients enrolled

Trial Details

Trial ID

NCT04411069

Start Date

February 20 2019

End Date

March 20 2021

Last Update

May 19 2021

Active Locations (1)

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Cancer Institute of the State of Sao Paulo - ICESP

São Paulo, São Paulo, Brazil, 01403010