Status:

COMPLETED

Cascade Genetic Testing of Familial Hypercholesterolemia

Lead Sponsor:

Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland

Collaborating Sponsors:

Swiss Heart Foundation

Conditions:

Familial Hypercholesterolemia

Eligibility:

All Genders

5+ years

Phase:

NA

Brief Summary

Familial hypercholesterolemia (FH) is a frequent genetic disorder (1/200) associated with an increased risk of early-onset myocardial infarction. To improve detection and treatment of patient with FH,...

Eligibility Criteria

Inclusion

  • patients with severe hypercholesterolemia and familial or personal history of early-onset cardiovascular disease = Dutch Lipid Clinic Network score (DLNC) \>= 6 points.

Exclusion

  • Patients without at least one contactable first-degree family members

Key Trial Info

Start Date :

November 10 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2023

Estimated Enrollment :

379 Patients enrolled

Trial Details

Trial ID

NCT04419090

Start Date

November 10 2020

End Date

December 31 2023

Last Update

January 18 2024

Active Locations (1)

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Center for primary care and public health (Unisanté), University of Lausanne

Lausanne, Switzerland, 1011