Status:
COMPLETED
Cardiac Magnetic Resonance Image (CMR) in Acute Carbon Monoxide (CO) Poisoning
Lead Sponsor:
Wonju Severance Christian Hospital
Collaborating Sponsors:
National Research Foundation of Korea
Conditions:
Carbon Monoxide Poisoning
Myocardial Injury
Eligibility:
All Genders
19+ years
Brief Summary
Previous report showed that 37% of patients with moderate to severe carbon monoxide (CO) poisoning experienced a myocardial injury, defined as elevated cardiac enzyme \[creatine kinase, CK-MB, and car...
Detailed Description
In the US, carbon monoxide (CO) poisoning accounts for 1,300 deaths and 50,000 emergency department visits annually. Previous report showed that 37% of patients with moderate to severe CO poisoning ex...
Eligibility Criteria
Inclusion
- Acute CO poisoning with myocardial injury, which was defined as elevated TnI (reference range \< 0.045 ng/mL), within 24 hours after ED arrival.
Exclusion
- Age \<19 years
- No elevated TnI within 24 hours after ED arrival
- Cardiac arrest upon ED arrival or before taking a CMR
- Co-ingestion of cardiac toxic drugs
- Transferred patients without admission
- Declined to enrollment in the study
- Impossible CMR due to artificial device
- Calculated creatinine clearance (Ccr) \< 30 mL/min
- Previous known history of hypersensitivity of gadolinium
- History of acute coronary syndrome, heart failure, or cardiomyopathy
- Patients who refuse CMR or fail to take a CMR although written informed consent was obtained
- Impossible of interpretation of CMR although CMR was taken
Key Trial Info
Start Date :
August 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 25 2020
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT04419298
Start Date
August 1 2017
End Date
May 25 2020
Last Update
June 5 2020
Active Locations (1)
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1
Wonju Severance Christian Hospital
Wŏnju, Gangwon-do, South Korea, 26426