Status:
UNKNOWN
Evaluate the Efficacy of Using Modified Qing-Ying Decoction in Atopic Dermatitis Children
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Atopic Dermatitis
Eligibility:
All Genders
4-17 years
Phase:
PHASE2
PHASE3
Brief Summary
The study aims to evaluate the clinical efficacy and safety of the modified Qing-Ying Decoction (mQYD) for the treatment of subacute and chronic atopic dermatitis (AD) in children when compared to the...
Detailed Description
The subjects will come for a screening visit at week 0 (baseline), then at week 6, week 12, and week 16 for Chinese medicine practitioner (CMP) investigators assessments. Eczema Area and Severity Inde...
Eligibility Criteria
Inclusion
- Age of 4 to 17 (Chinese only);
- With EASI ≥ 10;
- Subacute and chronic atopic dermatitis presenting with dry, scaly, erythematous papules and plaques; and
- Provide written informed consent form (signed by one of their parents)
Exclusion
- History of allergy to Chinese medicines;
- AD with Yang deficiency in syndrome differentiation, such as pale looking, always feeling cold, fatigue, chronic diarrhea with loose stool, urinary disorders such as urinary difficulty, excessive urination or incontinence
- Known overt bacterial infections in the skin;
- Known pregnancy;
- Known severe medical conditions, such as cardiovascular, liver or renal dysfunction or Diabetes Mellitus;
- Having used oral corticosteroids, oral antibiotics, other immunosuppressive or any preparation of oral herbal medicines for the treatment of AD in the past month;
- Having been diagnosed with scabies, allergic contact dermatitis, seborrheic dermatitis or psoriasis; and
- Has taken anti-coagulant or anti-platelet drugs in the past month.
- Has taken any probiotics, prebiotics in the last month
- Known history of glucose-6-phosphate dehydrogenase (G6PD) deficiency
Key Trial Info
Start Date :
September 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2023
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT04419584
Start Date
September 10 2020
End Date
May 1 2023
Last Update
June 22 2022
Active Locations (1)
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1
The Chinese University of Hong Kong
Hong Kong, Hong Kong