Status:
COMPLETED
Salvage HIFU for Local Recurrence in the Prostatic Bed After Prostatectomy and External Beam Radiation Therapy : Preliminary Results
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Prostatic Cancer
Eligibility:
MALE
60-86 years
Brief Summary
Retrospective monocentric analysis performed on patients treated with salvage HIFU for isolated macroscopic recurrence in the prostatic bed after radical prostatectomy and salvage or adjuvant EBRT. Th...
Eligibility Criteria
Inclusion
- patient treated by S-HIFU for a single recurrence within the prostatic bed after an initial RP with curative intent with or without lymphadenectomy followed by salvage or adjuvant EBRT (with or without pelvic lymph node irradiation) combined or not with ADT;
- life expectancy of ≥10 years;
- histological local recurrence (positive biopsy),
- negative metastatic evaluation (All patients underwent multiparametric MRI (mpMRI) to confirm the relapse in the prostatic bed and Choline PET/CT to exclude metastasis (lymph node, visceral or bone metastasis).
- the use of ADT at BF after S-EBRT was not an exclusion criterion (ADT was introduced by the centre referring the patient).
- no limits were placed on prostate cancer characteristics, PSA (value, doubling time (PSA-DT)), Gleason score and location of suspected recurrence in relation to the sphincter.
Exclusion
- patients who do not meet the inclusion criteria
Key Trial Info
Start Date :
March 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2020
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT04421781
Start Date
March 1 2020
End Date
June 1 2020
Last Update
June 9 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Urology and Transplantation Surgery, Edouard Herriot Hospital,
Lyon, France