Status:
UNKNOWN
The Disorder of Circadian Clock Gene and Early Cognitive Dysfunction After General Anesthesia
Lead Sponsor:
Shengjing Hospital
Conditions:
Postoperative Delirium
General Anesthesia
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Postoperative cognitive dysfunction (POCD) is a common postoperative complication in patients aged 65 and over, which refers to cognitive function changes such as memory decline and attention deficit ...
Eligibility Criteria
Inclusion
- patients whose age ≥ 18 years old and \<90 years of preoperative sleep disorder;
- Primary cancer patients who had not received any radiotherapy or chemotherapy before surgery;
- Surgeries expected to be performed under general anesthesia after ≧3 hours
Exclusion
- a history of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis;
- inability to communicate due to coma, severe dementia, language impairment or serious illness;
- critically ill (preoperative ASA (American Society of Anesthesiologists)\>III), Childe-Pugh C or severe renal insufficiency (preoperative dialysis);
- Neurosurgery.
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT04421872
Start Date
July 1 2020
End Date
December 31 2023
Last Update
June 9 2020
Active Locations (1)
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1
Junchao Zhu
Shenyang, China, 110004