Status:

RECRUITING

Tofacitinib in Adult Patients With Moderate to Severe Ulcerative Colitis

Lead Sponsor:

Pfizer

Conditions:

Ulcerative Colitis

Eligibility:

All Genders

18+ years

Brief Summary

This is an observational prospective study with two years of follow-up, designed to evaluate the effectiveness of tofacitinib in patients with moderate to severe ulcerative colitis in French clinical ...

Detailed Description

TO FAst is a non-interventional study in France with primary objective to describe the clinical benefit of tofacitinib 1 year after its initiation for the treatment of moderate to severe UC in routine...

Eligibility Criteria

Inclusion

  • Patients of 18 years old or above
  • Patients with confirmed diagnosis of moderate to severe ulcerative colitis
  • Patients for whom gastroenterologist decides to initiate treatment with tofacitinib as per the French SmPC
  • Patients informed about the study procedures and receiving an information letter signed by the investigator

Exclusion

  • Patients who have already received tofacitinib treatment before baseline
  • Patients that fulfill any of the contrindications according to the latest version of the SmPC

Key Trial Info

Start Date :

December 4 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 15 2025

Estimated Enrollment :

280 Patients enrolled

Trial Details

Trial ID

NCT04424303

Start Date

December 4 2020

End Date

December 15 2025

Last Update

November 17 2025

Active Locations (38)

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Page 1 of 10 (38 locations)

1

Clinique de l Europe

Amiens, France, 80090

2

Hopital Sud

Amiens, France, 80480

3

Hopital Jean Minjoz

Besançon, France, 25003

4

Hopital de La Cote de Nacre

Caen, France, 14027