Status:
RECRUITING
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Lead Sponsor:
Laureate Institute for Brain Research, Inc.
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Anxiety
Depression
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Depression and anxiety disorders rank in the top ten causes of years lived with disability. Less than 50% of patients experiencing long-lasting improvements to current gold-standard treatments. Two go...
Eligibility Criteria
Inclusion
- score \>55 on both the PROMIS Anxiety and PROMIS Depression scales
- score \>5 on any one item of the SDS
- able to provide informed consent
- report of anxiety and depressive symptoms as areas of clinical concern
- sufficient English proficiency to complete procedures.
Exclusion
- significant or unstable physical or mental health conditions (e.g., immediate suicidal intent) requiring medical attention
- history of bipolar, psychotic, cognitive, obsessive compulsive disorder, posttraumatic stress disorder (PTSD)
- history of moderate to severe substance use disorder over the past year
- diagnosis of neurologic disorders
- MRI contra-indications (e.g., metal in body)
- uncorrected vision/hearing problems
- current, regular benzodiazepine use
Key Trial Info
Start Date :
September 11 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT04426461
Start Date
September 11 2020
End Date
June 30 2025
Last Update
June 13 2025
Active Locations (1)
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1
Laureate Institute for Brain Research
Tulsa, Oklahoma, United States, 74136