Status:
UNKNOWN
Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery
Lead Sponsor:
St. Joseph's Healthcare Hamilton
Conditions:
Postoperative Pain
Thyroid Diseases
Eligibility:
All Genders
18-100 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to compare the efficacy of Bupivicaine and Lidocaine for postoperative pain control in thyroid surgery.
Detailed Description
Patients planned for total thyroidectomy will be recruited for participation. After being informed about the study and potential risks, all patients giving written informed consent will be screened fo...
Eligibility Criteria
Inclusion
- Diagnosis of thyroid disease (malignant tumors T1-T3/NX-N1a, benign tumors)
- Planned for thyroid surgery with midline neck incision (total thyroidectomy, completion thyroidectomy, with or without central neck dissection)
- Will be admitted for at least 12h postoperatively
Exclusion
- Thyroid cancer staged as T4 (invasion, anaplastic) or requiring sternotomy
- Thyroid cancer staged as N1b (cervical, retropharyngeal, superior mediastinal nodal involvement)
- Previous ipsilateral thyroid surgery to operation side
- Previous total thyroidectomy or completion thyroidectomy
- History of neck radiation therapy
- Neck dissection beyond central neck (levels 1-5)
- Goiter extending beyond sternal notch (intrathoracic) or requiring sternotomy
- Surgery requiring extension of incision beyond 8 cm
- History of diabetes mellitus
- History of renal or liver disease
- History of narcotic abuse
- History of chronic pain medications use in past 6 months for any condition
- History of coagulation defect
- Allergy to Bupivacaine or Lidocaine
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT04427904
Start Date
June 1 2022
End Date
December 31 2025
Last Update
November 28 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
St. Joeseph's Healthcare Hamilton
Hamilton, Ontario, Canada, L8N4A6