Status:

ACTIVE_NOT_RECRUITING

The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery

Lead Sponsor:

Rijnstate Hospital

Conditions:

Bariatric Surgery

Morbid Obesity

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Bariatric guidelines recommend preoperative weight loss of 5% to reduce the risk of surgical complications. However, results in the literature on the improvement of surgical procedure and outcomes are...

Eligibility Criteria

Inclusion

  • Undergoing primary RYGB surgery (meeting all criteria + approval of surgeon)
  • Able to prepare the meal replacements at home

Exclusion

  • Undergoing another bariatric procedure than primary RYGB.
  • Diabetes Mellitus
  • Contraindication for the usage of Modifast meal replacements:
  • Allergy or intolerance to any substance in the used meal replacements (Soy, milk, gluten, egg, peanuts, nuts and seeds)
  • Veganism
  • Kidney failure (GFR \< 90 ml/min/1.73m2), liver failure or cardiac insufficiency
  • A heart attack (myocardial infarct) in the past twelve months
  • Cancer
  • Hypokalaemia: serum potassium level \<3.4 mmol/l
  • Phenylketonuria \& Porphyria

Key Trial Info

Start Date :

September 29 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2027

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04433338

Start Date

September 29 2020

End Date

July 1 2027

Last Update

January 3 2025

Active Locations (1)

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Rijnstate Hospital

Arnhem, Gelderland, Netherlands, 6811AD