Status:
UNKNOWN
Post Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients
Lead Sponsor:
Hamad Medical Corporation
Conditions:
COVID 19
Eligibility:
All Genders
18-60 years
Phase:
PHASE2
PHASE3
Brief Summary
More cases of COVID-19 pandemic are being reported daily around the world. It is highly infectious and, over 7 million people have been infected and more than 400,000 people have died globally till th...
Detailed Description
More cases of COVID-19 pandemic are being reported daily around the world. It is highly infectious and, over 7 million people have been infected and more than 400,000 people have died globally till th...
Eligibility Criteria
Inclusion
- 18 years or older, all healthcare workers in direct contact with COVID-19 patients (ex: physicians, nurses, pharmacists, etc.), the ability to swallow Oral medications, without any GI abnormalities that may affect absorption. Who agree to participate in the trial.
Exclusion
- Allergy to HCQ.
- Pregnancy or breastfeeding.
- Known history of Retinal disease not related to Macular degeneration, or preexisting eye retinopathy.
- Having a prior history of blood disorders such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia.
- Having a prior history of glucose-6-phosphate dehydrogenase (G-6-PD) deficiency.
- Having dermatitis, psoriasis, or porphyria.
- History of lung disease or Pneumonia not related to COVID-19.
- Taking CYP450 enzyme-inducing medications within 4 weeks of the start of taking HCQ (Ex: Phenytoin, Carbamazepine, Phenobarbital, Primidone or Oxcarbazepine.
- Currently taking QT-prolonging medications, which may include Antiarrhythmics, Quinolones, Macrolides, select Antipsychotics and Antidepressants.
- Team members planning to have major abdominal, thoracic, spine or CNS surgery during the protocol period
Key Trial Info
Start Date :
August 31 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT04437693
Start Date
August 31 2020
End Date
December 31 2021
Last Update
August 11 2020
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