Status:

UNKNOWN

Prognostication of Oxygen Requirement in Non-severe SARS-CoV-2 Infection

Lead Sponsor:

Medecins Sans Frontieres, Spain

Collaborating Sponsors:

Mahidol Oxford Tropical Medicine Research Unit

International Centre for Diarrhoeal Disease Research, Bangladesh

Conditions:

SARS-CoV2

COVID

Eligibility:

All Genders

18+ years

Brief Summary

Note that this is a study that is co-sponsored by Medecins Sans Frontieres, Spain, and the University of Oxford. The primary objective of this study is to identify clinical and biochemical prognostic...

Detailed Description

Background At the time of writing the novel betacoronavirus SARS-CoV-2 has infected more than 11 million individuals and killed more than 500,000. The most recent epidemiological surveillance curve s...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • The participant may enter the study if ALL of the following apply:
  • Aged ≥ 18 years, and willing and able to give informed consent and comply with study procedures;
  • RT-PCR or antigen test positive for SARS-CoV-2 during current illness
  • Systemic manifestation of SARS-CoV-2 infection defined as:
  • Breathing difficulty
  • OR
  • History of fever during current illness AND chest pain OR abdominal pain OR loose stool OR severe myalgia
  • Exclusion Criteria
  • The participant may not enter the study if ANY of the following apply:
  • Requires supplemental oxygen or mechanical ventilation (invasive / non-invasive) at presentation;
  • Laboratory confirmed SARS-CoV-2 infection (virological or serological) during a previous illness episode.
  • Documented history of Vaccination for SARS-Cov-2

Exclusion

    Key Trial Info

    Start Date :

    October 1 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2021

    Estimated Enrollment :

    600 Patients enrolled

    Trial Details

    Trial ID

    NCT04441372

    Start Date

    October 1 2020

    End Date

    December 1 2021

    Last Update

    October 1 2021

    Active Locations (3)

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    Page 1 of 1 (3 locations)

    1

    Foundation for Scientific and Technological Development in Health (FIOTEC)

    Rio de Janeiro, Brazil, 4036

    2

    All India Institute of Medical Sciences Patna (AIIMS)

    Patna, Bihar, India, 801507

    3

    Christian Medical College, Vellore

    Vellore, Tamil Nadu, India, 632004