Status:
COMPLETED
Comparison of Intermittent Fasting and Caloric Deficit for Weight Loss in Women With Polycystic Ovarian Syndrome
Lead Sponsor:
Karachi Medical and Dental College
Collaborating Sponsors:
Aziz Medical Center
Conditions:
Polycystic Ovarian Syndrome
Weight Loss
Eligibility:
FEMALE
20-35 years
Phase:
NA
Brief Summary
Time restricted feeding (TRF) has been emerging as a potential weight loss strategy that avoids major dietary changes but achieves strong effects. It also improves insulin sensitivity through increase...
Eligibility Criteria
Inclusion
- PCOS as described by Rotterdam's criteria
Exclusion
- endocrine disorders
- diabetic
- hypertensive
- Taking medications affecting weight or energy intake/energy expenditure in the last 6 months, including weight loss medications, antipsychotic drugs or other medications as determined by the study physician;
- The body weight fluctuated more than 5% in recent 3 months.
- Liver and kidney dysfunction: renal impairment, creatinine clearance rate \< 30 mL/min/1.73 m2, transaminase increased, more than three times higher than the normal limit;
- History of serious cardiovascular or cerebrovascular disease (angina, myocardial infarction or stroke) in the past 6 months;
- History of thyroid diseases;
- pregnant
- Currently participating in weight loss programs or weight change in the past 3 months (\> 5% current body weight)
- Patients who cannot be followed for 16 months (due to a health situation or migration)
- Patients who are unwilling or unable to give informed consent
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2020
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT04452968
Start Date
July 1 2020
End Date
October 30 2020
Last Update
November 25 2020
Active Locations (1)
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1
Aziz Medical Center
Karachi, Sindh, Pakistan, 74600