Status:
TERMINATED
Endometrial Compaction and Its Influence on Pregnancy Rate in Frozen Embryo Cycle Regimes
Lead Sponsor:
ART Fertility Clinics LLC
Conditions:
Endometrial Disorder
Infertility, Female
Eligibility:
FEMALE
18-40 years
Brief Summary
For a pregnancy to occur, an euploid embryo at blastocyst developmental stage, a receptive endometrium and the synchrony of both is crucial. Many studies lately investigated the influence of the endom...
Detailed Description
Further on, the measurement of the endometrial thickness was mostly performed either on the day of final oocyte maturation in stimulated cycles with fresh embryo transfer or on the day of progesterone...
Eligibility Criteria
Inclusion
- Women aged 18 years to 40 years with regular menses (26-34 days)
- Having 1 or 2 chromosomally normal cryopreserved blastocysts available for transfer after IVF / ICSI treatment
- First frozen-thawed transfer cycle
- Progesterone level \< 1.5 ng/mL day of trigger injection in stimulation cycle from which embryos to be transferred were created.
Exclusion
- Polycystic ovarian syndrome
- Poor ovarian responder in accordance with Bologna criteria
- Uterine abnormality US / saline infusion sonohysterogram
- Previous dilatation \& curettage (D\&C)
- Hydrosalpinx
- Asherman syndrome
- History of endometriosis AFS ≥ 2
- ICSI due to severe male factor with testicular sperm
- Any known contraindications or allergy to oral estradiol or progesterone.
- Discontinuation of HRT medication ( medication error in research HRT cycle )
- Failure to detect ovulation in the research natural cycle
- Ovulation after day 20 in a natural cycle
- Duration of estradiol exposure ≥ 17 days and endometrium \< 6mm
- Spontaneous ovulation in HRT artificial cycle
Key Trial Info
Start Date :
November 9 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 4 2021
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT04454749
Start Date
November 9 2020
End Date
March 4 2021
Last Update
March 8 2021
Active Locations (1)
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1
IVI Middle East Fertility Clinic
Abu Dhabi, United Arab Emirates, 60202