Status:
TERMINATED
Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI
Lead Sponsor:
Jonsson Comprehensive Cancer Center
Conditions:
Malignant Brain Neoplasm
Eligibility:
All Genders
Phase:
NA
Brief Summary
This trial looks to study the safety and feasibility of using oxygen-enhanced molecular MRI to understand how cancer cells use oxygen differently than normal cells. Cancer cells tend to utilize (or no...
Detailed Description
PRIMARY OBJECTIVES: I. Determine the safety, feasibility, and sensitivity of oxygen-enhanced molecular magnetic resonance imaging (MRI) in healthy volunteers. II. Measure oxygen-enhanced molecular M...
Eligibility Criteria
Inclusion
- Healthy volunteers will include persons who at the time of scans do not present with known neurological conditions that might impact tissue imaging results
- Patient participants should have suspected or pathology-confirmed diagnosis of a brain tumor (any histological subtype including brain metastases)
- All participants must be able to obtain an MRI scan and must be able to safely breathe high concentrations of oxygen
Exclusion
- Participants with contraindications to MRI including metal implants
- Participants who are deemed not able to or not safe to breath high concentrations of oxygen
Key Trial Info
Start Date :
July 7 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 16 2021
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04460495
Start Date
July 7 2020
End Date
September 16 2021
Last Update
May 10 2022
Active Locations (1)
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1
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States, 90095