Status:
RECRUITING
Observational Study for the Evaluation of Incidence of Familial AML/MDSs in Patients With Myeloid Neoplasms
Lead Sponsor:
Gruppo Italiano Malattie EMatologiche dell'Adulto
Conditions:
Acute Myeloid Leukemia
Familial Acute Myeloid Leukemia
Eligibility:
All Genders
18+ years
Brief Summary
Observational study aimed at evaluating the incidence of familial AML/MDSs in patients with de novo MDSs or AML with almost one relative affected by hematologic neoplasms and/or other cancers at young...
Detailed Description
This is a multicenter, retrospective and prospective, observational study aims to collect clinical information on patients with familial AML/MDSs from January 2014 to December 2022. No intervention is...
Eligibility Criteria
Inclusion
- Patient age \> 18 years old
- Diagnosis of AML or MDSs from January 2014 to December 2022
- Suspected familiarity for myeloid neoplasm: at least one family member of first or second degree affected by myeloid neoplasm or other hematological malignancy, or by solid tumors with onset at age \< 40 years or presence of signs, symptoms or laboratory tests compatible with one of the known syndromes with germinal susceptibility to AML/MDSs
- Signed written informed consent according to ICH/EU/GCP and national local laws.
Exclusion
- none
Key Trial Info
Start Date :
December 16 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
237 Patients enrolled
Trial Details
Trial ID
NCT04460950
Start Date
December 16 2020
End Date
March 1 2025
Last Update
April 10 2024
Active Locations (27)
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1
Aon Ss. Antonio E Biagio E C. Arrigo - Alessandria - Soc Ematologia
Alessandria, Italy
2
Aou Ospedali Riuniti "Umberto I - G.M. Lancisi - G. Salesi"- Ancona - Sod Clinica Ematologica
Ancona, Italy
3
Ao Di Rilievo Nazionale E Di Alta Specialità "San Giuseppe Moscati" - Avellino - Uoc Ematologia Con Unità Di Trapianto
Avellino, Italy
4
Asl Caserta, Presidio Ospedaliero S.G.Moscati - Aversa - Uo Oncoematologia
Aversa, Italy