Status:

COMPLETED

Comparison Between Latanoprost , Travoprost and Tafluprost in Reducing IOP Fluctuation in POAG Patients

Lead Sponsor:

Kasr El Aini Hospital

Conditions:

Primary Open Angle Glaucoma

Eligibility:

All Genders

18+ years

Brief Summary

Elevated IOP is a key risk factor for the progression of glaucoma. IOP is subjected to diurnal fluctuation in healthy individuals and higher fluctuation in POAG . So, once-daily antiglaucoma drugs mus...

Eligibility Criteria

Inclusion

  • Both genders aged 18 years or more.
  • Newly diagnosed POAG cases having :
  • IOP more than 21 mmHg Open angle on gonioscopy Showing both structural and functional damage (confirmed with OCT and visual field)

Exclusion

  • Angle closure glaucoma.
  • Secondary glaucomas.
  • Advanced glaucoma likely to be uncontrolled on monotherapy or needing a low target IOP.
  • History of ocular trauma, laser or intraocular surgery.
  • Any other ocular disorder including uveitis and cystoid macular edema.
  • Known history of allergy or sensitivity to any components of the study medications.

Key Trial Info

Start Date :

June 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2020

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04461249

Start Date

June 1 2019

End Date

April 1 2020

Last Update

July 8 2020

Active Locations (1)

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1

Kasr El-Aini hospital

Cairo, Egypt