Status:

UNKNOWN

GFAP Auto-immunity : a French Cohort Study

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Autoimmune GFAP Astrocytopathy

Eligibility:

All Genders

Brief Summary

Glial fibrillary acidic protein (GFAP)-Immunoglobulin G (IgG) have recently been described as a biomarker of a novel inflammatory central nervous system (CNS) disorder, termed autoimmune GFAP astrocyt...

Eligibility Criteria

Inclusion

  • Positive GFAP-Ab in serum and/or CSF tested by immunohistochemistry on mouse brain slices and confirmed by cell-based assay (CBA) of HEK293 cells expressing GFAP.
  • Diagnosis and follow-up in France
  • No age limit : from 0 to unlimited age

Exclusion

  • Patients GFAP-IgG negative in serum and CSF
  • Absence of complete clinicopathological data
  • Foreign follow-up

Key Trial Info

Start Date :

September 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2020

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT04463550

Start Date

September 1 2019

End Date

November 1 2020

Last Update

July 9 2020

Active Locations (1)

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1

Hospices Civils de Lyon

Bron, France, 69250

GFAP Auto-immunity : a French Cohort Study | DecenTrialz