Status:

TERMINATED

Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment

Lead Sponsor:

Midwest Eye Institute

Collaborating Sponsors:

Ocular Therapeutix, Inc.

Conditions:

Retinal Detachment

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This prospective, open-label, single-center, randomized, investigator-sponsored clinical study seeks to investigate: how will pseudophakic patients respond in terms of objective and subjective outcome...

Detailed Description

Subjects who have given informed consent and determined to be eligible at screening will be randomized in a 1:1 ratio to DEXTENZA (placed once in the lower punctum) or the use of topical Prednisolone ...

Eligibility Criteria

Inclusion

  • Pseudophakic
  • Retinal Detachment
  • Age 18 years and older
  • Scheduled for gas bubble repair and laser surgery following retinal detachment
  • Willing and able to comply with clinic visits and study related procedures
  • Willing and able to sign the informed consent form

Exclusion

  • Patients under the age of 18.
  • Pregnancy (must be ruled out in women of child-bearing age with pregnancy test)
  • Active infectious systemic disease
  • Active infectious ocular or extraocular disease
  • Obstructed nasolacrimal duct in the study eye(s)
  • Hypersensitivity to dexamethasone
  • Patients being treated with immunomodulating agents in the study eye(s)
  • Patients being treated with immunosuppressants and/or oral steroids
  • Patients with severe disease that warrants critical attention, deemed unsafe for the study by the investigator

Key Trial Info

Start Date :

July 14 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 25 2023

Estimated Enrollment :

7 Patients enrolled

Trial Details

Trial ID

NCT04464629

Start Date

July 14 2020

End Date

January 25 2023

Last Update

August 16 2023

Active Locations (1)

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Midwest Eye Institute

Indianapolis, Indiana, United States, 46290