Status:

RECRUITING

Better Leukemia Diagnostics Through AI (BELUGA)

Lead Sponsor:

Munich Leukemia Laboratory

Conditions:

Hematologic Malignancy

Leukemia

Eligibility:

All Genders

18+ years

Brief Summary

To the best of our knowledge, BELUGA will be the first prospective trial investigating the usefulness of deep learning-based hematologic diagnostic algorithms. Taking advantage of an unprecedented col...

Detailed Description

In numerous recent studies, deep neuronal networks (DNN) have been leveraged to examine the usefulness of artificial intelligence (AI)-based DNN for diagnostic purposes. In essence, they have successf...

Eligibility Criteria

Inclusion

  • Patients having been diagnosed with a suspected hematological disorder
  • The suspected diagnoses constitute a primary diagnosis
  • Only samples of patients min.18 years of age will be used
  • Samples must suffice quality attributes which are denoted in "Exclusion Criteria"

Exclusion

  • The sample is not fit for state-of-the-art diagnosis or fails initial quality control. For quality insurance, we will exclude samples in heparin- instead of EDTA. Samples with damage due to atmospheric reasons (freeze-thaw damage or elevated temperature) will be excluded.
  • Samples with too scarce material jeopardizing routine gold-standard diagnosis will be excluded.
  • Bone marrow aspirates without sufficient material to assess malignant or healthy hematopoiesis.

Key Trial Info

Start Date :

January 5 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2025

Estimated Enrollment :

25000 Patients enrolled

Trial Details

Trial ID

NCT04466059

Start Date

January 5 2020

End Date

July 31 2025

Last Update

December 17 2024

Active Locations (1)

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MLL Munich Leukemia Laboratory

Munich, Bavaria, Germany, 81377