Status:
COMPLETED
CLOSE Versus High Density Mapping Guided Catheter Ablation of Paroxysmal Atrial Fibrillation
Lead Sponsor:
University Medical Centre Ljubljana
Conditions:
Pulmonary Vein Isolation
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The aim of this study is to compare two methods of catheter ablation for treatment of paroxysmal atrial fibrillation (AF). The first method being a modified CLOSE protocol used for the control group a...
Detailed Description
CLOSE protocol is among the latest methods of catheter ablation of AF. According to this protocol, ablations are guided by ablation index, which takes into account ablation time, the contact force and...
Eligibility Criteria
Inclusion
- electrocardiographic evidence of paroxysmal AF in the last six months,
- unsuccessful treatment with antiarrhythmic drugs or highly symptomatic arrhythmia episodes (EHRA 3 and 4).
Exclusion
- age over 80 years,
- greatly enlarged left atrium (ultrasound parasternal diameter more than 50 mm),
- life expectancy less than one year,
- acute life-threatening disease,
- previous heart surgery,
- severe left or right ventricular dysfunction (LVEF equal or less than 35 %),
- severe valve failure,
- presence of a clot in the left atrium,
- previous atrial fibrillation ablation
Key Trial Info
Start Date :
February 26 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04466358
Start Date
February 26 2021
End Date
October 1 2024
Last Update
October 16 2024
Active Locations (1)
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1
UMC Ljubljana
Ljubljana, Slovenia, 1000