Status:

UNKNOWN

The Impact of Moderate Versus Deep Neuromuscular Blockade on Enhanced Recovery After Bariatric Anesthesia

Lead Sponsor:

King Saud University

Conditions:

Bariatric Surgery Candidate

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Most published articles suggest that deep neuromuscular blockade is required for bariatric surgery. However, the evidence for such practice is still inconclusive. From the clinical experience at a maj...

Detailed Description

Muscle relaxation is paramount for successful laparoscopic surgery. However the optimal degree of neuromuscular blockade (NMB) is not identified yet. Previous studies showed conflicting results on the...

Eligibility Criteria

Inclusion

  • Age older than 18 years.
  • Obese or morbidly obese as defined by a BMI \> 35 (kg/m2).
  • American Society of Anesthesiologists physical status class II, or III.
  • Presenting of Laparoscopic sleeve gastrectomy.

Exclusion

  • History of allergy to Rocuronium or Sugammadex.
  • History of allergy to Dexamethasone, Ondansetron, Paracetamol, Fentanyl, Propofol, Morphine or Tramadol.
  • Current or previous pregnancy.
  • History of renal impairment, (We are going to use the Cockcroft-Gault equation is the gold standard for estimating renal function for the purposes of drug dosing cut off point: CrCl/GFR=30ml/min) The GFR calculator is available at: http://clincalc.com/Kinetics/CrCl.aspx?example
  • Patient on oxygen therapy , e,g CPAP

Key Trial Info

Start Date :

January 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2020

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT04466943

Start Date

January 1 2020

End Date

December 31 2020

Last Update

July 10 2020

Active Locations (1)

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1

King Saud University College of Medicine and King Khalid University Hospital

Riyadh, Saudi Arabia, 11472