Status:
RECRUITING
Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Conditions:
Follicular Lymphoma
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The researchers are doing this study to measure and test cell-free DNA (cfDNA) in the blood before, during, and after first-line treatment for follicular lymphoma. They will look at whether cfDNA leve...
Detailed Description
This is a non-therapeutic protocol aimed to assess the ability of the s cfDNA assay to detect clinical response in FL when compared to conventional approaches for assessing response, such as PET-CT sc...
Eligibility Criteria
Inclusion
- ≥18 years of age at time of signing informed consent. Consent is permitted from either the participant or from a Legally Authorized Representative (LAR) on their behalf.
- Histology-confirmed follicular lymphoma grade 1-3a, verified by the enrolling institution
- Ability to adhere to the study visit schedule and all the protocol requirements
- Measurable FDG-avid disease
- Not applicable for retrospective patients in CR
Exclusion
- Patients receiving second or greater line of therapy (except in retrospective cohort of long-term survivors of FL \[i.e. \>10 years out from frontline treatment\])
Key Trial Info
Start Date :
July 8 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04468841
Start Date
July 8 2020
End Date
July 1 2026
Last Update
August 19 2025
Active Locations (7)
Enter a location and click search to find clinical trials sorted by distance.
1
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, United States, 07920
2
Memorial Sloan Kettering Monmouth (All protocol activities)
Middletown, New Jersey, United States, 07748
3
Memorial Sloan Kettering Bergen (All protocol Activities)
Montvale, New Jersey, United States, 07645
4
Memorial Sloan Kettering Commack (All Protocol Activities)
Commack, New York, United States, 11725