Status:
COMPLETED
Inflammation, Intracellular Invasion and Colonization of the Nasal Mucosa by Staphylococcus Aureus
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Conditions:
Healthy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
An inflammatory state of the nasal cells (very close to keratinocytes) could favour the internalization of Staphylococcus aureus and thus constitute a persistent reservoir for the carriage of this bac...
Detailed Description
The main objective is to compare the expression level of ICAM-1 in nasal cells with and without the presence of Staphylococcus aureus.
Eligibility Criteria
Inclusion
- Subject affiliated to a social security scheme or entitled person
- Subject who received informed information about the study et signed consent
- Adult subject (≥18ans)
- Healthy Volunteer
Exclusion
- Subject undergoing antibiotic treatment or having received antibiotic treatment (oral, IV or local) in the month prior to inclusion
- Subject with a major haemostasis disorder or anticoagulant treatment contraindicated for surgery
- Subject with a pathology increasing the nasal carriage of S. aureus (chronic furunculosis, diabetes, HIV infection, chronic rhinosinusitis)
- Subject under guardianship or trusteeship
- Pregnant woman
Key Trial Info
Start Date :
October 18 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 9 2023
Estimated Enrollment :
157 Patients enrolled
Trial Details
Trial ID
NCT04469348
Start Date
October 18 2021
End Date
January 9 2023
Last Update
May 23 2024
Active Locations (1)
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1
CHU de Saint-Etienne
Saint-Etienne, France