Status:
COMPLETED
A Retrospective Cohort Study: Influence of MTHFR C677T and A1298C Polymorphisms on the Survival of Pediatric Patients With Non-Hodgkin's Lymphoma
Lead Sponsor:
Sun Yat-sen University
Conditions:
Pediatric Non-Hodgkin Lymphoma
Eligibility:
All Genders
Up to 18 years
Brief Summary
The primary purpose of this retrospective study was to investigate the influence of methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphism on the survival of pediatric patients with Non...
Eligibility Criteria
Inclusion
- aged ≤ 18 years;
- newly diagnosed as the four main categories of NHL(Burkitt's lymphoma, lymphoblastic lymphoma, anaplastic large cell lymphoma, and diffuse large B-cell lymphoma) between 2014 and 2020;
- treated according to the modified BFM95 protocol.
Exclusion
- aged \> 18 years;
- not newly diagnosed as the four main categories of NHL between 2014 and 2020;
- treated according to chemotherapeutic regimens except for the modified BFM95 protocol.
Key Trial Info
Start Date :
January 20 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 20 2020
Estimated Enrollment :
374 Patients enrolled
Trial Details
Trial ID
NCT04469543
Start Date
January 20 2014
End Date
May 20 2020
Last Update
July 14 2020
Active Locations (1)
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1
Sun Yat-Sen University Cancer Center
Guangzhou, Guangdong, China, 510060