Status:

UNKNOWN

Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome

Lead Sponsor:

Universita di Verona

Conditions:

Psoriasis

Metabolic Syndrome

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

A prospective, controlled, open trial in psoriasis patients with metabolic syndrome, candidate to methotrexate or secukinumab was conducted between January 2019 and May 2020. The primary end point of ...

Detailed Description

A prospective, non-randomized controlled open trial in psoriasis patients with metabolic syndrome was conducted between January 2019 and May 2020. Inclusion criteria were age ≥ 18 years, being affecte...

Eligibility Criteria

Inclusion

  • age ≥ 18 years
  • being affected by moderate to severe chronic plaque psoriasis and concomitant metabolic syndrome
  • being candidate to systemic treatment with methotrexate or secukinumab according to the Italian guideline for psoriasis

Exclusion

  • being affected by psoriatic arthritis, pregnancy, breast feeding,
  • having initiated a systemic treatment for psoriasis in the previous 3 months and having a clinical condition that could affect the metabolic parameters other than metabolic syndrome.

Key Trial Info

Start Date :

August 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04469829

Start Date

August 1 2020

End Date

December 31 2022

Last Update

July 14 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Verona

Verona, Italy, 37126

Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome | DecenTrialz