Status:
UNKNOWN
Platinum Plus Low-dose Long-term Continuous Intravenous Infused 5-Fluorouracil in Metastatic Nasopharyngeal Carcinoma
Lead Sponsor:
Sun Yat-sen University
Conditions:
Nasopharyngeal Carcinoma
Metastasis
Eligibility:
All Genders
18-70 years
Brief Summary
The treatment of distant metastasis is a key challenge for nasopharyngeal carcinoma because of poor outcomes, among which, chemotherapy is the cornerstone. However, many studies reported the use of di...
Detailed Description
Nasopharyngeal carcinoma (NPC) is a malignant tumor of the nasopharyngeal epithelium with high sensitivity to ionizing radiation. With the use of intensive chemoradiotherapy, excellent treatment outco...
Eligibility Criteria
Inclusion
- Nasopharyngeal carcinoma diagnosed by pathology or cytology
- Distant metastasis confirmed by Radiographic assessments or pathology.
- Patients ever received systemic chemotherapy.
Exclusion
- Age \<18 or \>70 years old
- Pathologic type unknown or except type I-III of World Health Organization classification
- Never underwent platinum-based chemotherapy
- Lack of information about T classification and N classification when metastasis
- Lost follow-up within one month from the start of treatment for metastasis
- Without other malignances
Key Trial Info
Start Date :
November 26 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT04472403
Start Date
November 26 2019
End Date
December 1 2020
Last Update
July 20 2020
Active Locations (1)
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1
Department of Radiation Oncology, Sun Yat-Sen University Cancer Center
Guangzhou, Guangdong, China, 510060