Status:
COMPLETED
Assessment of Lung Recruitablity of Acute Respiratory Distress Syndrome With SARS-CoV-2 Pneumonia by Electrical Impedance Tomography
Lead Sponsor:
Osaka University
Collaborating Sponsors:
Hospital Rebagliati
Conditions:
Critical Illness
ARDS
Eligibility:
All Genders
18+ years
Brief Summary
Novel coronavirus (SARS-CoV-2: severe acute respiratory coronavirus 2) pneumonia often develop the acute respiratory distress syndrome (ARDS). Lung protective ventilation strategy consisting of low ti...
Detailed Description
The multi-center prospective observational study will enroll 20 adult ARDS patients under mechanical ventilation from Intensive Care Units (ICUs) in Japan and Peru. Informed consent will be waived due...
Eligibility Criteria
Inclusion
- Patients with positive SARS-CoV-2 infection＊
- Patients with ARDS under mechanical ventilation＊＊
- Patients ≧ 18 years old
- Definition of SARS-CoV-2 infection positive: SARS-CoV-2 infection is defined as being positive in RT-PCR (real time reverse transcriptase-polymerase chain reaction) assay using nasal or pharyngeal swab samples.
- Definition of ARDS is as per the Berlin definition (PaO2/FiO2 ≦ 300 mmHg with PEEP ≧ 5 cmH2O)
Exclusion
- Contraindication for EIT monitoring
- Unstable spine or pelvic fractures
- Pacemaker, automatic implantable cardioverter defibrillator
- Skin lesions between the 4th and 5th ribs where the EIT belt is worn
- Home mechanical ventilation before inclusion
- Pregnancy
- DNR (do-not-resuscitate)
- Increased intracranial pressure (\> 18 mmHg)
Key Trial Info
Start Date :
May 11 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2021
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT04473300
Start Date
May 11 2020
End Date
February 28 2021
Last Update
July 1 2021
Active Locations (1)
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1
Osaka University Hospital
Suita, Osaka, Japan, 565-0871