Status:
COMPLETED
Prone Positioning in Non-intubated Patients With COVID-19 Associated Acute Respiratory Failure
Lead Sponsor:
Hospital Civil de Guadalajara
Conditions:
Covid19
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Besides protective ventilation with low tidal volumes, prone positioning is a proven intervention to decrease mortality in mechanically ventilated patients with moderate-severe acute respiratory distr...
Detailed Description
Despite ongoing trials of antivirals and immunomodulatory therapies against COVID-19, the treatment of moderate/severe disease is mainly supportive, including oxygen therapy and invasive mechanical ve...
Eligibility Criteria
Inclusion
- Adult patients with confirmed COVID-19, and requirement of a fraction of inspired oxygen (FiO2) ≥30% through high-flow nasal cannula (HFNC) to maintain a capillary saturation of ≥90%
Exclusion
- Less than 18 years-old
- Pregnancy
- Patients with immediate need of invasive mechanical ventilation
- Contraindications for prone positioning therapy
- Do-not-resuscitate or do-not-intubate order
- Refusal of the patient or decision maker to enroll in the study
Key Trial Info
Start Date :
May 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 26 2021
Estimated Enrollment :
430 Patients enrolled
Trial Details
Trial ID
NCT04477655
Start Date
May 3 2020
End Date
January 26 2021
Last Update
April 13 2021
Active Locations (2)
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1
Hospital Civil Fray Antonio Alcalde
Guadalajara, Jalisco, Mexico, 44280
2
Hospital General de Occidente
Guadalajara, Jalisco, Mexico, 45170