Status:

RECRUITING

Advanced Translational Research on Childhood Leukemia

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Childhood Leukemia

Eligibility:

All Genders

Up to 18 years

Brief Summary

Prognosis of children with leukemia, the most common pediatric cancer, has improved markedly. Yet, relapse still occurs in 15-40% of patients with a probability of survival of \<50%, which is unlikely...

Detailed Description

The first part of the study aimed to investigate genomics and drug sensitivity profiling of childhood leukemia and its potential application for precision medicine. The second part of the study aimed...

Eligibility Criteria

Inclusion

  • List of inclusion criteria:
  • acute lymphoblastic leukemia (ALL) or
  • acute myeloid leukemia (AML) or
  • 3 .mixed phenotype acute leukemia (MPAL) or
  • 4\. juvenile myelomonocytic leukemia (JMML) or
  • 5\. myelodysplastic syndromes (MDS) or
  • 6\. normal bone marrow donor
  • List of exclusion criteria:
  • This study will not recruit subjects who are unable to understand English or Chinese.
  • Patient or parent refusal

Exclusion

    Key Trial Info

    Start Date :

    July 1 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 1 2026

    Estimated Enrollment :

    150 Patients enrolled

    Trial Details

    Trial ID

    NCT04478006

    Start Date

    July 1 2020

    End Date

    June 1 2026

    Last Update

    June 20 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Hong Kong Children Hospital

    Hong Kong, Hksar, China