Status:

COMPLETED

Establishment and Characterization of Meningioma Patient-derived Organoids

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Meningioma

Eligibility:

All Genders

18+ years

Brief Summary

In this study, meningioma organoids will be established from patients' tissues and the characterization of the organoid will be performed.

Detailed Description

Aims and Hypothesis to be tested: The investigators hypothesized that the derived organoid should have a similar morphological and genetic mutation signatures to the patient primary tissue. Study pe...

Eligibility Criteria

Inclusion

  • Adult patients (aged \>18 years) with meningioma
  • Admission into Prince Wales hospitals neurosurgical services
  • Patients with surgical needs of meningioma removal

Exclusion

  • 1\. Patients (or next-of-kin as appropriate) refuse to participate into the study

Key Trial Info

Start Date :

May 23 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 31 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04478877

Start Date

May 23 2020

End Date

August 31 2023

Last Update

September 7 2023

Active Locations (1)

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1

Department of Surgery, The Chinese University of Hong Kong

Hong Kong, Hong Kong