Status:
COMPLETED
Neuroprotection During Open Heart Surgery
Lead Sponsor:
ghada fouad
Conditions:
Open Heart Surgery
Eligibility:
All Genders
30-70 years
Phase:
PHASE3
Brief Summary
Millions of individuals with coronary artery, or valvular heart disease have been given a new chance at life by heart surgery, but the potential for neurological injury is a great risk .Neural complic...
Detailed Description
The aim of the study is to evaluate neuroprotective effect of mixture of propofol and ketamine (ketofol) as compared to propofol after open heart surgery. Induction; * Pre-oxygenation with100% O2 fo...
Eligibility Criteria
Inclusion
- Age between 30 and 70 years of either sex.
- Patients scheduled for elective cardiac surgery using cardiopulmonary bypass (CPB) either valve surgery or coronary artery bypass surgery
Exclusion
- Patient refusal.
- Morbidly obese patients.
- Patients with uncontrolled diabetes.
- Patients with pre-existing neurological disease or using anti-psychotics. Severe or uncontrolled renal, hepatic or endocrinal diseases.
- Pregnancy, post-partum or lactating females
- Allergy to one of the agents used.
- Emergency cardiac surgery.
- Re-do surgery.
Key Trial Info
Start Date :
July 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2017
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04486690
Start Date
July 1 2016
End Date
June 30 2017
Last Update
July 24 2020
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