Status:

COMPLETED

Restylane® for the Treatment of Tear Trough Deformity

Lead Sponsor:

Erevna Innovations Inc.

Conditions:

Tear Trough Eyelid Deformity

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The aim of this study is to investigate the effectiveness and tolerability of Restylane® for correction of tear trough deformity, using various injection techniques.

Eligibility Criteria

Inclusion

  • Female;
  • Age of 18 years or greater;
  • Indication for treatment of bilateral tear trough deformity;
  • Symmetry of tear trough deformity at baseline;
  • Subjects who understood and signed the Informed Consent Form (ICF) when entering the study, before performing any investigational procedure.

Exclusion

  • Prior (\<1 year) or planning to undergo any surgery in the corporal area of interest for study;
  • Any type of comorbidity or clinical condition that, at investigator's discretion, could interfere with study assessments;
  • Diabetes mellitus type 1 or type 2;
  • Autoimmune diseases, collagenosis, decompensated endocrine diseases or any disease that, at investigator's discretion, could interfere with study assessments;
  • Using or have used within 3 months drugs such as corticosteroids, immunosuppressants or others collagen-production inhibitors;
  • Initiated use of hormones or change in dose of hormonal replacement therapy within 3 months;
  • Pregnant or breastfeeding, or wishes to get pregnant within the next 12 months, or refuses to use appropriate contraceptive method (in case of women of childbearing potential);
  • Restylane® should not be used in any person who has hypersensitivity to any of the components of the product;
  • Active skin inflammation or infection in or near the treatment area;
  • Possessing any of the contraindications for use of Restylane®;
  • Septal fat herniation;
  • Severe elastosis (e.g., dermatochalasis);
  • Use of Vitamin E, gingko biloba, Aspirin or non-steroidal anti-inflammatory drugs (NSAIDS) within 1 week of treatment.
  • Use of tear trough injections in the last 12 months.
  • Use of anterior midface injections in the last 12 months.

Key Trial Info

Start Date :

July 7 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2020

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT04486794

Start Date

July 7 2019

End Date

December 31 2020

Last Update

February 10 2021

Active Locations (1)

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1

Erevna Innovations Inc

Montreal, Quebec, Canada, H3R 3A1