Status:

UNKNOWN

Screening of Gastrointestinal Tract Bleeding Causes Among Chronic Renal Failure Patients

Lead Sponsor:

Assiut University

Conditions:

CKD

GIT - Gastrointestinal Tract Hemorrhage

Eligibility:

All Genders

Brief Summary

The aim of the current study is to screen different causes and characteristics of Gastrointestinal bleeding in Chronic Renal Failure patients at Assuit University Hospital according to their stages ba...

Detailed Description

* Chronic Renal Failure is defined as presence of reduced glomerular filtration rate (GFR) \< 60 ml/min/ 1.73 m2 and/or evidence of kidney damage (usually indicated by albuminuria or proteinuria) for ...

Eligibility Criteria

Inclusion

  • One hundred Chronic Renal Failure patients with different stages (stage I to IV) according to the National Kidney Foundation are recruited from inpatients of renal unit in internal medicine department, Assuit university hospitals. Their GFR will assessed by using Chronic Renal Failure EPI equation measured as GFR=166 x(s cr/0.7)-1.209X(0.993)age if female, and GFR=163X(s cr/0.9)-1.209x(0.993)age if male. (Andrews et al 2008).
  • Chronic Renal Failure staging according to GFR by Chronic Renal Failure EPI is:
  • Stage1 in which GFR\>90 mil/min but evidence of kidney damage.
  • Stage 2 GFR 60-89 mil/min.
  • Stage 3 GFR 30-95 mil/min.
  • Stage 4 GFR 15-29 mil/min.
  • Stage 5 GFR\<15 mil/min.

Exclusion

  • All Patients with local causes of Gastrointestinal Bleeding
  • Benign and Malignant tumors in Gastrointestinal Tract.
  • Patients with Hemorrhoids or anal fissures.
  • Patients with Mallory-Weiss tears.
  • patients with Diverticular disease.
  • patients with Colon polyps.
  • patients with infectious causes of GIT bleeding (Salmonella, Shigella)
  • patients with Angiodysplasia.
  • patients with Esophageal varices

Key Trial Info

Start Date :

October 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04491669

Start Date

October 1 2020

End Date

December 1 2021

Last Update

July 29 2020

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