Status:
UNKNOWN
Tui-na and Oral Chinese Medicine on KOA
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
The study aims to evaluate the therapeutic effect of the Tui-na and oral Chinese medicine on the treatment of KOA. This is a prospective, randomized wait-list controlled trial in patients with knee o...
Detailed Description
The subjects will come for a screening visit at week 0 (baseline), then at week 2, week 4, and week 8 for Chinese medicine practitioner (CMP) investigators assessments. The Western Ontario and McMaste...
Eligibility Criteria
Inclusion
- of either gender (female must have either sterilization done or menopause)
- ≥50years of age
- meet the criteria of KOA according to the American College of Rheumatology
- Knee pain, and
- Any 4 of the following,
- ≥ 50 years of age
- Less than 30 minutes of morning stiffness
- Crepitus on active motion
- Bony tenderness
- Bony enlargement
- No palpable warmth of synovium
- Osteophytes (Radiographic findings)
- with WOMAC score ≥ 39
- with written informed consentform signed (for illiterate subjects, their next-of-kin or an impartial witness will sign with subjects' permission)
Exclusion
- Known knee pain caused by infection, malignant or autoimmune diseases
- Knee surgery or arthroscopy in the past year
- Chondroprotective or intra-articular injection in the past 4 months
- Systemic corticoid treatment in the past 4 months
- Taking anticoagulants, antiplatelets, corticosteroids, psychiatric drugs, hormones, antiarrhythmic drugs or diuretics drugs
- Subject with uncontrolled hypertension
- Local antiphlogistic treatment, acupuncture, physiotherapy in the past 2 weeks
- Known history of mental disorder
- Known history of serious acute organic disease
- Renal or liver function impairment
- Known allergy to or have drug interaction with the study herb
Key Trial Info
Start Date :
September 14 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04492670
Start Date
September 14 2020
End Date
March 1 2023
Last Update
June 22 2022
Active Locations (1)
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1
The Chinese University of Hong Kong
Hong Kong, Hong Kong