Status:
COMPLETED
Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections
Lead Sponsor:
Vanderbilt University Medical Center
Collaborating Sponsors:
University of British Columbia
University of California, San Diego
Conditions:
Urinary Tract Infections
Kidney Stone
Eligibility:
All Genders
18+ years
Brief Summary
This study will assess patients who have recurrent urinary tract infections and kidney stones which are not blocking the kidney or causing other problems. Currently, we don't know if taking out these ...
Detailed Description
Urinary tract infections (UTIs) are common and have a large burden of disease at the population level. This study will assess the effectiveness of removing kidney stones in patients who have recurrent...
Eligibility Criteria
Inclusion
- Inclusion Criteria (all of the following):
- recurrent UTIs, defined as 3 positive urine cultures of specific organisms with symptoms within 12 months (or 2 positive cultures with symptoms within 6 months) prior to clinical assessment
- non-obstructing renal stone(s) on imaging within 6 months of initial visit
- Exclusion Criteria:
- age \< 18 years
- pregnancy
- hydronephrosis or evidence of obstruction
- presence of a foreign body in urinary tract (e.g. Foley, ureteral stent, nephrostomy tube) at the time of UTI diagnosis
- concurrent bladder calculi
- Urinary diversion or previous surgery involving segments of bowel interposed into the urinary tract (ileal conduit, ileal ureter etc.)
Exclusion
Key Trial Info
Start Date :
September 9 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2025
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT04495699
Start Date
September 9 2020
End Date
September 1 2025
Last Update
October 21 2025
Active Locations (6)
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1
Mayo Clinic Arizona
Phoenix, Arizona, United States, 85054
2
University of California San Diego
San Diego, California, United States, 92093
3
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
4
Columbia University
New York, New York, United States, 10027