Status:

COMPLETED

Efficacy of PoNS in Reducing Symptoms of Multiple Sclerosis

Lead Sponsor:

Helius Medical Inc

Collaborating Sponsors:

McGill University

Conditions:

Multiple Sclerosis

Eligibility:

All Genders

28-62 years

Phase:

NA

Brief Summary

The purpose of this pilot study is to determine whether a program involving both in-lab and at-home training using cranial nerve stimulation (CN-NINM) delivered via the tongue can reduce symptoms of m...

Detailed Description

Fourteen MS patients, seven each in an active and a sham stimulation group are expected to participate. Participants will receive intensive physical therapy and working memory training for 14 weeks. ...

Eligibility Criteria

Inclusion

  • Relapsing/remitting or secondary progressive MS with balance and gait problems;
  • Recent EDSS score of 3.0 - 6.0;
  • Provided informed consent and willing to participate

Exclusion

  • Use of tobacco products;
  • Oral health problems including abrasions, cuts, cold sores, piercings, or tissue inflammation in the oral cavity;
  • Baseline EDSS \>6.

Key Trial Info

Start Date :

December 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2016

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT04496531

Start Date

December 1 2014

End Date

August 1 2016

Last Update

August 5 2020

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