Status:
UNKNOWN
Efficacy of Transcranial Direct Current Stimulation (tDCS) for the Treatment of Major Depressive Disorder
Lead Sponsor:
Tianjin Anding Hospital
Conditions:
Major Depressive Disorders
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The aim of this study is to assess the efficacy of Transcranial Direct Current Stimulation (tDCS) as an Add-on Treatment for the drug-naïve Major depressive disorder. Meanwhile, evaluate the effect of...
Detailed Description
This is a randomized, double-blind, sham-controlled study using transcranial Direct Current Stimulation (tDCS) for 4-week treatment. After the intervention of tDCS, there is a follow up visit at week ...
Eligibility Criteria
Inclusion
- a current episode of MDD diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
- age between 18 and 50 years
- a total score of HAMD-17 ≥ 17
- take antidepressants less than 3 days
- Patients are compliant with treatment according to the judgement of the treating clinician.
- Participant or guardian has to sign informed consent. The patients' guardians will sign the informed consent on behalf of the participants when the capacity of participants to consent is compromised.
Exclusion
- A history of manic episode
- Use of mood stabilizer
- History of substance abuse or dependence
- Severe somatic diseases that might interfere with regular antidepressant treatment including conditions such as kidney and liver failure, uncontrolled hypertension, cardiovascular, cerebrovascular and pulmonary disease, thyroid disease, diabetes, epilepsy and asthma.
- Use of anti-inflammatory medication for longer than 7 days in the last two months preceding the trial
- Use of immunosuppressive medication such as oral steroid hormones Women in pregnancy or lactation period
Key Trial Info
Start Date :
May 22 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT04497493
Start Date
May 22 2020
End Date
March 1 2023
Last Update
October 19 2021
Active Locations (1)
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1
Tianjin Anding Hospital
Tianjin, China