Status:
COMPLETED
Efficacy of Neural Prolotherapy in Treatment of Meralgia Paresthetica
Lead Sponsor:
University of Alexandria
Conditions:
Meralgia Paresthetica
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Meralgia paresthetica is an entrapment neuropathy of the lateral femoral cutaneous nerve. Its main manifestation is neuropathic pain on the lateral aspect of the thigh. Neural prolotherapy has shown i...
Detailed Description
Meralgia paresthetica is a mononeuropathy of the lateral femoral cutaneous nerve (i.e. lateral cutaneous nerve of the thigh). It is known as the lateral cutaneous nerve of the thigh neuralgia. It is d...
Eligibility Criteria
Inclusion
- The patients had clinical evidence of meralgia paresthetica which was based on the following: (i) the presence of pain, paraesthesia and numbness over the anterior and lateral aspect of the thigh; (ii) exacerbation of these symptoms on walking, standing and hip extension; and (iii) meralgia paresthetica was confirmed electrophysiologically by nerve conduction study with or without somatosensory evoked potentials.
- The symptoms needed to be present for at least three months.
- The patients should be unresponsive to conservative treatment. The conservative treatment included lifestyle modification including weight reduction, activity modification (avoid the use of seat belts) and avoidance of tight underwear (tight garments such as jeans, uniforms); non-steroidal anti-inflammatory drugs and anticonvulsants for neuropathic pain; and physiotherapy.
Exclusion
- Diabetes mellitus.
- Endocrine disorders.
- Metabolic disorders.
- Systemic rheumatologic disorders.
- Neurological disorders including peripheral neuropathy, lumbar radiculopathy and lumbar plexopathy.
- Coagulopathy.
- Anticoagulant treatment.
- Current skin or soft tissue infection at or near the site of injection.
- Prior local injection of corticosteroid in the past year for meralgia paresthetica.
- Prior neural prolotherapy in the past year for meralgia paresthetica.
- Prior surgery in the affected thigh region.
- Patients presented with a systemic active inflammatory condition or infection.
- Pregnancy.
- Patients refused to participate in the study
Key Trial Info
Start Date :
April 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2019
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04499911
Start Date
April 15 2018
End Date
September 30 2019
Last Update
August 5 2020
Active Locations (1)
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1
Faculty of Medicine, Alexandria University
Alexandria, Egypt, 21131