Status:
UNKNOWN
Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals
Lead Sponsor:
Texas Woman's University
Conditions:
Stroke
Multiple Sclerosis
Eligibility:
All Genders
21-90 years
Brief Summary
Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills...
Detailed Description
The walking after stroke called "hemiparetic gait" is characterized by slow and asymmetrical steps with poor motor control on the paretic leg while paradoxically increasing the cost of energy expendit...
Eligibility Criteria
Inclusion
- Healthy adults have no ongoing neurological, musculoskeletal issues.
- Individuals with chronic stroke had medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment.
- Individuals have multiple sclerosis disease diagnosed by his/her physician
- MRI or CT evidence from the imaging report shown that the stroke and multiple sclerosis disease primarily involve cortical and subcortical regions.
- Individuals with chronic stroke have hemiparesis involving the lower extremity.
- Individuals with chronic stroke or multiple sclerosis have no passive range of motion limitation in bilateral hips and knees. Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less.
- Visual acuity can be corrected by glasses or contact lens to 20/20.
- Able to walk independently with/without assistant devices for 10 meters.
- Able to maintain standing position without any assistance for more than 30 sec.
- Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24.
Exclusion
- Pregnant women.
- MRI or CT evidence of involvement of the basal ganglia or cerebellum, or evidence of any other brain damage or malignant neoplasm or tumors.
- Have any metal implants, cardiac pacemakers, or history of seizures.
- Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training.
- Any vestibular dysfunction or unstable angina.
- Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia\*
Key Trial Info
Start Date :
April 4 2013
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT04503187
Start Date
April 4 2013
End Date
December 31 2024
Last Update
August 7 2020
Active Locations (1)
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1
Texas Woman's University
Houston, Texas, United States, 77030